Collection Method
CI05.15.01
Kit Requirements
Serum
Turn Around Time
24 hours Turnaround times are estimates
Description
Insulin resistance (IR) is a condition characterised by resistance to the effects of insulin at a cellular level. Muscle and adipose tissue require increasing greater amounts of insulin to transfer sugars from the bloodstream. Higher levels of pancreatic insulin synthesis are required to maintain normal blood levels and, therefore both fasting and post-prandial glucose levels rise. Increasing HOMA scores reflect this. Untreated insulin resistance may lead to diabetes and require medical intervention and ongoing treatment.
Insulin Resistance is calculated from both the fasting insulin and fasting glucose results to create the HOMA score (homoeostasis model assessment of insulin resistance).
Insulin resistance is a key component of the Metabolic Syndrome along with abdominal obesity, elevated LDL cholesterol and triglyceride levels, low HDL cholesterol and high blood pressure.
A strong family history of diabetes is a major risk factor for high levels of insulin resistance, along with high GI carbohydrates intake including excessive alcohol consumption; lack of regular exercise; stress and nutritional deficiencies such as chromium, vanadium and magnesium.
References:
Nagpal M, De D, Handa S, Pal A, Sachdeva N. Insulin Resistance and Metabolic Syndrome in Young Men With Acne. JAMA Dermatol. 2016;152(4):399‐404. doi:10.1001/jamadermatol.2015.4499
Carvalho CA, Silva AAM, Assunção MCF, et al. The dietary inflammatory index and insulin resistance or metabolic syndrome in young adults. Nutrition. 2019;58:187‐193. doi:10.1016/j.nut.2018.07.014
Analytes
- Fasting Glucose
- fasting Insulin
- HOMA-IR score (homoeostasis model assessment of insulin resistance)
Test Method
Automated chemistry (Roche Diagnostics)
Common Conditions
Cardiovascular Health- Cardiovascular Disease
- Hypercholesterolaemia
- Hypertension
- Hypertriglyceridaemia
Nutritional and Dietary Symptoms- Obesity
Endocrine and Hormonal Health- Pre-diabetes
Notice To Patients
NutriPATH practices in the usual practitioner-referral system for pathology laboratories. Patients are highly recommended to seek the supervision and guidance of a qualified healthcare practitioner for the interpretation of any lab results and associated information. NutriPATH can offer assistance in locating a suitable practitioner.
How it works
Step 1
Order test
Your referring practitioner will place this order via their online portal.
Step 2
Collect Samples
A test kit will be dispatched to you and you can conveniently collect your sample in the comfort of your home.
Step 3
Return Samples
Return samples for analysis via the provided courier packaging.
Patient resources
Our highly skilled and qualified team have created a service where patients can easily gain access to a wide range of pathology testing options.
Practitioner resources
As a leader in the industry, practitioners are able to trust in our ability to provide them with the technology they need to adequately test their clients and patients.
