Zonulin in recent years has been discovered as an effective tool for monitoring the levels of zonulin as elevated levels of this protein are identified to be the potential doorway to leaky gut syndrome, chron’s and other inflammation, autoimmunity and gastro-intestinal diseases.
The Zonulin pathway has been exploited to deliver drugs, macromolecules, or vaccines that normally would not be absorbed through the gastrointestinal mucosal barrier. However, if the tightly regulated trafficking of macromolecules is jeopardized secondary to prolonged Zonulin up-regulation, the excessive flow of antigens in the intestinal mucosa can cause both intestinal and extra-intestinal autoimmune disorders in genetically susceptible individuals.
Common Conditions:
- Leaky gut
- Bacterial infection
- Parasitic infection
- IBS
- Chron’s disease
- Diabetes
- Ankyosing spondylitis
- Schizophrenia
- Neoplastic disease
- Pancreatic cancer
- Gilioma
- Asthma
